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Wintrobe's Clinical Hematology 12th Revised edition [Kietas viršelis]

Edited by , Edited by , Edited by , Edited by , Edited by , Edited by , Edited by
  • Formatas: Hardback, 3232 pages, aukštis x plotis: 280x216 mm, weight: 8262 g, 1425 illustrations
  • Išleidimo metai: 17-Dec-2008
  • Leidėjas: Lippincott Williams and Wilkins
  • ISBN-10: 0781765072
  • ISBN-13: 9780781765077
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 3232 pages, aukštis x plotis: 280x216 mm, weight: 8262 g, 1425 illustrations
  • Išleidimo metai: 17-Dec-2008
  • Leidėjas: Lippincott Williams and Wilkins
  • ISBN-10: 0781765072
  • ISBN-13: 9780781765077
Kitos knygos pagal šią temą:

Established since 1942 as the leading hematology textbook, Wintrobe's Clinical Hematology is now in its thoroughly revised Twelfth Edition. The text continues its tradition of correlating basic science with the clinical practice of hematology and is organized to help physicians find clinical answers quickly and easily.

The Twelfth Edition is in full color for the first time, includes more international contributors, and has two new editors, Daniel A. Arber, MD and Robert T. Means, Jr., MD. Highlights include expanded coverage of molecular genetics and pathogenesis, more hematopathology illustrations, and current information on new medications and their rapid bench-to-bedside development. Four new chapters cover anemias unique to the newborn period, pathology of LHC and other histiocytic disorders, tumors of the spleen, and pathology and classification of myeloproliferative disorders and mast cell disease.

A companion Website will offer the fully searchable text and an image bank.



Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology continues to be an industry leader with its ability to correlate basic science with the clinical practice of hematology. With the first edition of Wintrobe's Clinical Hematology published in 1942 clearly establishing hematology as a distinct subspecialty of Internal Medicine, the latest edition continues the influence of the Wintrobe name and helps to set this book apart from the competition. With its strong focus on the clinical aspects of hematology, the book has generated a strong following among internists and general practitioners who want a single resource to consult for their patients who present any blood related disorder. The Twelfth Edition is in full color for the first time, boasts a new editorial team, and includes expanded coverage of new medications and four new chapters on Newborn Anemias, Pathology of LHC, Spleen Tumors, and Myeloproliferative Disorders and Mast Cell Disease. A companion Website will offer the fully searchable text and an image bank.

Recenzijos

Journal of the American Medical Association (JAMA), 09-DEC-09, Volume 302, Issue 22, Paulette Mehta, MD, MPH, Departments of Hematology/Oncology, University of Arkansas for Medical Sciences, Central Arkansas Veterans Healthcare System -- "This is the 12th and most complete iteration of Wintrobe's Clinical Hematology, first published in 1942 by Maxwell Meyer Wintrobe, a leading hematologist at that time. In the years since, the book has been updated, the science elaborated, and the number of editors expanded. Yet subsequent editions have retained the strength of the first edition...The current editorial team consists of the 5 experts who edited the previous edition, along with 2 new editors. All are experts in pediatric or adult hematology/hematopathology, and all are located in North America. More than 150 author-experts have contributed. "The book is encyclopedic in its coverage of biology and pathophysiology as well as of clinical practice. It is one of the largest hematology textbooks, comprising 2 volumes totaling 2606 pages. It offers an exhaustive panorama of diagrams, figures, standard and electron micrographs, algorithms, schemas, and protocols-all in color... "Chapters on hematologic malignancies are up to date and include new and potential future treatments. Treatment regimens are schematized and compared and contrasted with each other. For example, the protocols for leukemia are shown in parallel using color-coded blocks, making for easy and comparison of different regimens and helping clinicians to design their own protocols as needed based on benefits and toxicities. Juxtaposition of chromosome and genomic features with hematologic clinical features and prognoses are helpful for scientists and clinicians alike. The book is current and provides descriptions of novel agents and of emerging treatments in the pipeline. All chapters are consistent in style, format, and referencing. Figures abound-there are 1 to 5 figures per page, intermixed with the text. Tables are uniform in style throughout. "The book is accompanied by an electronic edition, also in full color, providing the complete text and all of the figures, schemas, and tables. The electronic content is fully searchable by topic, citation, author, or keyword. The tables and figures are useful for reviewing a chapter or presenting material to peers. Readers will find little information about geriatric hematology or stem cell transplantation; however, specialized textbooks are available in each of those topics. What readers of Wintrobe's Clinical Hematology will find is a comprehensive, encyclopedic, accurate, and authoritative review of classic hematology that exquisitely intertwines basic molecular biology with the clinical diagnosis and treatment of disease."-Journal of the American Medical Association (JAMA)

Contributors xi
Preface xix
Acknowledgments xxi
Introduction xxiii
VOLUME 1
PART I Laboratory Hematology
Examination of the Blood and Bone Marrow
1(20)
Sherrie L. Perkins
Clinical Flow Cytometry
21(29)
Frixos Paraskevas
Cytogenetics
50(20)
Sheila N. J. Sait
Maria R. Baer
Molecular Biology and Hematology
70(9)
Rebecca L. Shattuck-Brandt
Stephen J. Brandt
PART II The Normal Hematologic System
Hematopoiesis
Origin and Development of Blood Cells
79(27)
Mark J. Koury
Nadim Mahmud
Melissa M. Rhodes
The Erythrocyte
Erythropoiesis
106(20)
Emmanuel N. Dessypris
Stephen T. Sawyer
The Mature Erythrocyte
126(30)
Marilyn J. Telen
Destruction of Erythrocytes
156(14)
Bertil Glader
Granulocytes and Monocytes
Neutrophilic Leukocytes
170(44)
Keith M. Skubitz
The Human Eosinophil
214(22)
Redwan Moqbel
Solomon O. (Wole) Odemuyiwa
Paige Lacy
Darryl J. Adamko
Basophilic Leukocytes: Mast Cells and Basophils
236(13)
A. Dean Befus
Judah A. Denburg
Mononuclear Phagocytes
249(32)
Gregory A. Taylor
J. Brice Weinberg
Phagocytosis
281(19)
Frixos Paraskevas
The Lymphocytes
Lymphocytes and Lymphatic Organs
300(26)
Frixos Paraskevas
B Lymphocytes
326(32)
Frixos Paraskevas
T Lymphocytes and Natural Killer Cells
358(44)
Frixos Paraskevas
Effector Mechanisms in Immunity
402(66)
Frixos Paraskevas
Hemostasis
Megakaryocytes
468(22)
Kenneth Kaushansky
Platelet Structure and Function in Hemostasis and Thrombosis
490(38)
David C. Calverley
Christiane D. Thienelt
Blood Coagulation and Fibrinolysis
528(92)
Kathleen Brummel-Ziedins
Thomas Orfeo
Nancy Swords Jenny
Stephen J. Everse
Kenneth G. Mann
Endothelium: Angiogenesis and the Regulation of Hemostasis
620(11)
Paul J. Shami
George M. Rodgers
PART III Therapeutic Modalities
Red Cell, Platelet, and White Cell Antigens
631(41)
Kathryn E. Webert
James W. Smith
Donald M. Arnold
Howard H. W. Chan
Nancy M. Heddle
John G. Kelton
Transfusion Medicine
672(50)
Susan A. Galel
Dorothy D. Nguyen
Magali J. Fontaine
Lawrence Tim Goodnough
Maurene K. Viele
Hematopoietic Stem Cell Transplantation
722(27)
Vijayakrishna K. Gadi
Richard A. Nash
Gene Therapy for Hematologic Disorders
749(30)
John F. Tisdale
Jay N. Lozier
Stacey A. Goodman
Cynthia E. Dunbar
PART IV Disorders of Red Cells
Introduction
Anemia: General Considerations
779(31)
Robert T. Means, Jr.
Bertil Glader
Disorders of Iron Metabolism and Heme Synthesis
Iron Deficiency and Related Disorders
810(25)
Nancy C. Andrews
Sideroblastic Anemias
835(22)
Sylvia S. Bottomley
Hemochromatosis
857(24)
Corwin Q. Edwards
Porphyria
881(30)
Sylvia S. Bottomley
Hemolytic Anemia
Hereditary Spherocytosis, Hereditary Elliptocytosis, and Other Disorders Associated with Abnormalities of the Erythrocyte Membrane
911(22)
Patrick G. Gallagher
Bertil Glader
Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders
933(23)
Bertil Glader
Autoimmune Hemolytic Anemia
956(22)
Richard C. Friedberg
Vandita P. Johari
Alloimmune Hemolytic Disease of the Fetus and Newborn
978(20)
Anne F. Eder
Catherine S. Manno
Paroxysmal Nocturnal Hemoglobinuria
998(23)
Charles J. Parker
Russell E. Ware
Acquired Nonimmune Hemolytic Disorders
1021(17)
Robert T. Means, Jr.
Bertil Glader
Hereditary Disorders of Hemoglobin Structure and Synthesis
Sickle Cell Anemia and Other Sickling Syndromes
1038(45)
Winfred C. Wang
Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis
1083(49)
Caterina Borgna-Pignatti
Renzo Galanello
Hemoglobins with Altered Oxygen Affinity, Unstable Hemoglobins, M-Hemoglobins, and Dyshemoglobinemias
1132(11)
Martin H. Steinberg
Other Red Cells Disorders
Megaloblastic Anemias: Disorders of Impaired DNA Synthesis
1143(30)
Ralph Carmel
Inherited Aplastic Anemia Syndromes
1173(12)
Akiko Shimamura
Blanche P. Alter
Acquired Aplastic Anemia
1185(11)
Robert A. Brodsky
Red Cell Aplasia
1196(16)
Emmanuel N. Dessypris
Jeffrey M. Lipton
Congenital Dyserythropoietic Anemias
1212(9)
Sunitha N. Wickramasinghe
Bertil Glader
Anemias Secondary to Chronic Disease and Systemic Disorders
1221(18)
Robert T. Means, Jr.
Anemias During Pregnancy and the Postpartum Period
1239(8)
Robert T. Means, Jr.
Anemias Unique to the Newborn Period
1247(14)
Robert D. Christensen
Robin K. Ohls
Erythrocytosis
1261(12)
Robert T. Means, Jr.
VOLUME 2
PART V Disorders of Hemostasis and Coagulation
Introduction
Diagnostic Approach to the Bleeding Disorders
1273(16)
George M. Rodgers
Christopher M. Lehman
Thrombocytopenia
Thrombocytopenia: Pathophysiology and Classification
1289(3)
George M. Rodgers
Thrombocytopenia Caused by Immunologic Platelet Destruction
1292(22)
Christiane D. Thienelt
David C. Calverley
Thrombotic Thrombocytopenic Purpura, Hemolytic-Uremic Syndrome, and Related Disorders
1314(12)
Han-Mou Tsai
Miscellaneous Causes of Thrombocytopenia
1326(9)
Neeraj Agarwal
George M. Rodgers
Other Disorders of Primary Hemostasis
Bleeding Disorders Caused by Vascular Abnormalities
1335(17)
Matthew M. Rees
George M. Rodgers
Essential Thrombocythemia and Thrombocytosis
1352(9)
Ayalew Tefferi
Qualitative Disorders of Platelet Function
1361(18)
Thomas J. Kunicki
Diane J. Nugent
Coagulation Disorders
Inherited Coagulation Disorders
1379(46)
Kenneth D. Friedman
George M. Rodgers
Acquired Coagulation Disorders
1425(39)
George M. Rodgers
Thrombosis
Thrombosis and Antithrombotic Therapy
1464(45)
Steven R. Deitcher
George M. Rodgers
PART VI Nonmalignant Disorders of Leukocytes, the Spleen, and/or Immunoglobins
Diagnostic Approach to Malignant and Nonmalignant Disorders of the Phagocytic and Immune Systems
1509(18)
Thomas L. McCurley
John P. Greer
Neutropenia
1527(21)
Raymond G. Watts
Qualitative Disorders of Leukocytes
1548(17)
Keith M. Skubitz
Abnormalities of the Monocyte-Macrophage System: The Lysosomal Storage Diseases
1565(7)
Margaret M. McGovern
Robert J. Desnick
Langerhans Cell Histiocytosis
1572(10)
Suman Malempati
H. Stacy Nicholson
Pathology of Langerhans Cell Histiocytosis and Other Histiocytic Proliferations
1582(7)
Lawrence M. Weiss
Karen L. Chang
Infectious Mononucleosis and Other Epstein-Barr Virus-Related Disorders
1589(23)
Thomas G. Gross
Primary Immunodeficiency Syndromes
1612(11)
Anthony R. Hayward
Acquired Immunodeficiency Syndrome
1623(14)
Elaine M. Sloand
Jerome E. Groopman
Disorders of the Spleen
1637(18)
Matthew R. Porembka
M. B. Majella Doyle
William C. Chapman
Tumors of the Spleen
1655(8)
Daniel A. Arber
PART VII Hematologic Malignancies
General Aspects
Hematopoietic Tumors: Principles of Pathologic Diagnosis
1663(6)
Daniel A. Arber
John B. Cousar
Complications of Hematopoietic Neoplasms
1669(25)
Madan H. Jagasia
Principles and Pharmacology of Chemotherapy
1694(27)
Kenneth R. Hande
Immunotherapy
1721(26)
Adetola A. Kassim
Sattva S. Neelapu
Larry W. Kwak
Luc Van Kaer
Supportive Care in Hematologic Malignancies
1747(44)
Madhuri Vusirikala
The Acute Leukemias
Molecular Genetics of Acute Leukemia
1791(17)
Mary Ann Thompson
Diagnosis and Classification of the Acute Leukemias and Myelodysplastic Syndrome
1808(12)
David R. Head
Acute Lymphoblastic Leukemia in Adults
1820(23)
Haruka Itakura
Steven E. Coutre
Acute Myeloid Leukemia in Adults
1843(46)
Maria R. Baer
John P. Greer
Acute Lymphoblastic Leukemia in Children
1889(29)
James A. Whitlock
Paul S. Gaynon
Acute Myelogenous Leukemia in Children
1918(20)
Robert J. Arceci
Richard Aplenc
Acute Promyelocytic Leukemia
1938(18)
Steven L. Soignet
Peter G. Maslak
Myelodysplastic Syndromes
1956(32)
Alan F. List
Avery A. Sandberg
Donald C. Doll
Myeloproliferative Disorders
Pathology of the Myeloproliferative Diseases
1988(18)
Tracy I. George
Chronic Myeloid Leukemia
2006(25)
Kaaren K. Reichard
Richard S. Larson
Ian Rabinowitz
Polycythemia Vera
2031(14)
Robert T. Means, Jr.
Primary Myelofibrosis
2045(9)
Ayalew Tefferi
Systemic Mastocytosis
2054(17)
Alexandra S. Worobec
Dean D. Metcalfe
Lymphoproliferative Disorders
Diagnosis and Classification of Lymphomas
2071(32)
William R. Macon
Thomas L. McCurley
Paul J. Kurtin
Ahmet Dogan
Molecular Genetic Aspects of Non-Hodgkin Lymphomagenesis
2103(41)
Stephan W. Morris
Andreas Rosenwald
Louis M. Staudt
Justus Duyster
Non-Hodgkin Lymphoma in Adults
2144(51)
John P. Greer
Michael E. Williams
Non-Hodgkin Lymphoma in Children
2195(19)
John T. Sandlund
Frederick G. Behm
Chronic Lymphocytic Leukemia
2214(42)
James B. Johnston
Matthew Seftel
Spencer B. Gibson
Hairy Cell Leukemia
2256(20)
David Szwajcer
James B. Johnston
Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome
2276(35)
John A. Zic
Amy C. Musiek
Claudio A. Mosse
John P. Greer
Hodgkin Lymphoma
2311(31)
Richard S. Stein
David S. Morgan
Plasma Cell Dyscrasias
Practical Aspects of the Clinical Approach to Patients with Monoclonal Immunoglobulin Disorders
2342(10)
Philip R. Greipp
Rafael Fonseca
Monoclonal Gammopathies of Undetermined Significance and Smoldering Multiple Myeloma
2352(20)
Robert A. Kyle
Multiple Myeloma
2372(67)
Angela Dispenzieri
Martha Q. Lacy
Philip R. Greipp
Immunoglobulin Light-Chain Amyloidosis (Primary Amyloidosis)
2439(32)
Morie A. Gertz
Martha Q. Lacy
Angela Dispenzieri
Suzanne R. Hayman
Waldenstrom Macroglobulinemia
2471(13)
Rafael Fonseca
Stephen M. Ansell
Cryoglobulinemia and Heavy Chain Disease
2484
Angela Dispenzieri
Morie A. Gertz
Thomas E. Witzig
Appendices
Appendix A. Clusters of Differentiation
2497(86)
Frixos Paraskevas
Appendix B. Normal Blood Values: Selected Health-associated Values for Neonatal, Pediatric, and Adult Populations
2583(12)
Sharon M. Geaghan
Appendix C. Comparative Hematology
2595
Harvey A. Ragan
Index 1