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Flow Cytometry in Neoplastic Hematology [Kietas viršelis]

  • Formatas: Hardback, 280 pages, aukštis x plotis: 246x189 mm, 150 black & white halftones, 140 colour illustrations, 10 colour line drawings
  • Išleidimo metai: 02-Feb-2006
  • Leidėjas: Informa Healthcare
  • ISBN-10: 1841845655
  • ISBN-13: 9781841845654
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 280 pages, aukštis x plotis: 246x189 mm, 150 black & white halftones, 140 colour illustrations, 10 colour line drawings
  • Išleidimo metai: 02-Feb-2006
  • Leidėjas: Informa Healthcare
  • ISBN-10: 1841845655
  • ISBN-13: 9781841845654
Kitos knygos pagal šią temą:
Flow cytometry is a fast means of reaching a diagnosis in many cases in hematopathology, and is becoming ever more popular as the front line in clinical practice, interesting even those with no basic training in its techniques. However, it is not always the only component necessary for an answer, so correlation with histomorphology is always welcome and often vital. Key features of this highly illustrated and practical guide include: comprehensive coverage of the aspects relevant for clinical diagnosis; an explanation of the general parameters useful in diagnosis with flow cytometry; correlation with color histomorphological findings throughout; a systematic approach from basic cases to complicated problem areas; and, focus on the clinical aspects, not just the technical background or procedural minutiae. All hematopathologists and neoplastic hematologists will find this an important resource for keeping up-to-date with developments in clinical practice.
Preface ix
Acknowledgments xi
Introduction
1(20)
Forward and side (orthogonal) scatter
2(2)
Flow cytometry of peripheral blood and bone marrow -- gating strategy
4(2)
Flow cytometry of lymph node and other 'solid' tissues -- exclusion of non-viable cells
6(9)
Intensity of staining and co-expression of antigens
15(5)
Aberrant expression of antigens
20(1)
Identification of clonal B cells
21(14)
Reactive lymph node (follicular hyperplasia)
21(1)
Clonal B-cell population
21(6)
Clonal B cells with no detectable surface immunoglobulins
27(7)
Additional markers in B-cell lymphomas
34(1)
Identification of abnormal T cells
35(16)
Forward scatter and pan-T antigen expression
35(3)
CD4--CD8 expression
38(9)
Additional markets in T-cell lymphoproliferations
47(2)
Mature T-cell disorders versus precursor T-lymphoblastic leukemia/lymphoma
49(2)
Identification of blasts
51(14)
Myeloblasts
52(7)
Lymphoblasts
59(2)
Thymocytes versus precursor T-lymphoblastic lymphoma
61(4)
Features of dyspoiesis
65(8)
Flow cytometry limitations
73(8)
Phenotypic markers
81(30)
CD2
81(1)
CD3
82(1)
CD4 and CD8
82(1)
CD5
83(1)
CD7
83(1)
CD10
83(7)
CD11b
90(1)
CD11c
90(1)
CD13 and CD33
90(1)
CD14
91(1)
CD15
91(2)
CD16
93(1)
CD19
93(1)
CD20
93(1)
CD21
93(3)
CD22
96(1)
CD23
96(1)
CD25
96(2)
CD30
98(1)
CD34
98(1)
CD38
99(1)
CD43
99(1)
CD45
99(1)
CD52
100(1)
CD56
100(1)
CD57
100(4)
CD64
104(1)
CD79 and CD81
104(1)
CD103
104(2)
CD117
106(1)
CD138
106(1)
FMC7
106(1)
HLA-DR
106(1)
TCR Gamma/delta
106(1)
TdT
106(1)
ZAP-70
106(5)
B-cell lymphoproliferations
111(44)
B-chronic lymphocytic leukemia/small lymphocytic lymphoma
112(15)
B-cell prolymphocytic leukemia
127(3)
Lymphoplasmacytic lymphoma/Waldenstrom's macroglobulinemia
130(1)
Marginal zone B-cell lymphoma
131(3)
Hairy cell leukemia
134(2)
Follicular lymphoma
136(4)
Mantle cell lymphoma
140(1)
Diffuse large B-cell lymphoma
141(2)
Primary effusion lymphoma
143(2)
Burkitt's lymphoma
145(6)
Plasma cell neoplasms
151(4)
Peripheral (mature/post-thymic) T-cell lymphoproliferations
155(26)
T-cell prolymphocytic leukemia
156(1)
Large granular lymphocyte leukemia
156(2)
Adult T-cell leukemia/lymphoma
158(1)
Aggressive NK-cell leukemia
158(1)
Extranodal NK/T-cell lymphoma, nasal type
158(2)
Enteropathy-type T-cell lymphoma
160(1)
Hepatosplenic T-cell lymphoma
160(1)
Peripheral T-cell lymphoma, unspecified
160(12)
Angioimmunoblastic T-cell lymphoma
172(1)
Anaplastic large cell lymphoma
172(4)
Cutaneous T-cell lymphomas
176(5)
Acute leukemia
181(40)
Acute myeloid leukemia
181(29)
Precursor B-lymphoblastic leukemia/lymphoma
210(2)
Precursor T-lymphoblastic leukemia/lymphoma
212(3)
Blastic NK-cell lymphoma (DC2 acute leukemia; plasmacytoid dendritic cell leukemia)
215(2)
Extramedullary myeloid tumor (granulocytic sarcoma)
217(2)
Biphenotypic acute leukemia
219(2)
Myelodysplastic syndromes and chronic myeloproliferative disorders
221(16)
Myelodysplastic syndromes
221(6)
Chronic myelomonocytic leukemia
227(1)
Chronic myeloproliferative disorders
227(10)
Abbreviations 237(2)
References 239(24)
Index 263